Neuroimaging and translational approaches
This area is dedicated to combining neuroimaging with other types of psychosocial approaches to identify neurocognitive factors that may help guide improvements in addictions treatment and prevention. With support and collaborations with the National Institute of Drug Abuse, the National Institute of Nursing Research, the CASAA Internal Awards program, and the Mind Research Network, CASAA scientists have been active in this area, evaluating the neural substrates underlying client and therapist language in motivational interviewing (MI) with adolescents and emerging adults using fMRI and MEG. Additionally, we are also using translational approaches to determine how neurodevelopment may influence adolescents' response to two risky sexual prevention programs (MI and Behavioral Skills Training; BST). Going forward, CASAA translational researchers will be investigating new methods to predict, diagnose and treat addictions using neuroimaging analyses. Specifically, proposals aim to evaluate the role of therapeutic mechanisms, peer factors, and parent behaviors in brain-based responses.
Specific areas of expertise include:
- Assessment of therapeutic response using fMRI and MEG
- Evaluations of neurodevelopment and adolescent-specific neuroimaging paradigms
- Development and testing of translational approaches (integrating basic biological and psychosocial factors)